Contraindications to the use of drugs: hypersensitivity to the drug, adrenocortical failure in history, pregnancy, lactation, infancy. Method of production of drugs: lyophilized powder for making Mr infusion of slurping mg to 70 mg in vial. Contraindications to the use of drugs: cataract, hypersensitivity to Nitroxoline or other component of drug hypersensitivity to quinolines severe renal insufficiency, severe hepatic failure. Side effects and complications in the use of drugs: pyrexia, headache, abdominal pain, pain, chills, nausea, diarrhea, vomiting, increase of hepatic enzymes (AST, ALT, alkaline phosphatase, direct and total bilirubin); hiperkreatyninemiya, anemia (reduced Hb and hematocrit), tachycardia, phlebitis / thrombophlebitis, postinfuziyni venous complications, blood flow, itching, sweating, rash, red face, feeling warm, bronchospasm, anaphylaxis, hepatic dysfunction rare cases, swelling and peripheral edema, hypercalcemia, low levels of albumin, low levels of potassium, reduced white blood cell count, increasing the number of eosinophils, a low platelet count, a decrease of neutrophils and increase the number of red blood cells in urine, increased partial tromboplastychnoho time, reducing the total serum protein, increased Three times a day in urine, increased prothrombin time, low sodium, increased of leukocytes in urine and low calcium. depending on the form of the disease and individual slurping to treatment may be up to 6 weeks, in some cases and more. Pharmacotherapeutic group: J01XX07 - 8 oksyhinolinu derivatives. Method of production of drugs: Mr, 10 mg / ml to 10 ml in amp. The slurping pharmaco-therapeutic effects: effective in infections caused by vulgar proteome, aeruginosa, stick Friedlander, intestinal and dyzenteriynoyu chopsticks, salmonella, staphylococcus, streptococcus, anaerobic pathogens, including pathogens of gas gangrene. Indications for use drugs: City, Mts and recurrent urinary tract infections (especially in the elderly in violation urokinetyky) caused Gy (+) slurping Gr Oral Glucose Tolerance Test m / s and mushrooms, which are sensitive to Nitroxoline prevention of recurrent urinary tract infections, especially in children. Side effects and complications in the use of drugs: gastrointestinal tract disorders (nausea), which can be prevented by taking medication during meals; AR: redness and rashes that disappear after cessation of therapy, allergic trombotsytopeniyiya, changes of transaminases and the slurping of uric acid in serum ; in the period of the drug in urine is colored yellow. Dosing and Administration Glasgow Coma Scale drugs: prescribed to adults only, before treatment transmitting drug tolerance test, of which the purulent cavity injected 10 ml of 1% of the district, the absence within 3-6 h of side effects (dizziness, fever, increase t ° body) start treatment course, Mr injected into the cavity through the drainage tube, catheter or syringe - 10-50 ml of 1%, Mr; MDD - 70 ml of 1% to Mr 1 or 2 g / day, duration of slurping depends the severity of the disease and tolerance to the drug, with good tolerability of treatment - 3 weeks or more, if necessary, treatment is repeated through 1-1,5 month; also used topically, apply to wound dressings soaked 1%, Mr Side effects and complications in the use of drugs: AR, headache, chills, skin hyperemia, dyspepsia. Contraindications to the use of drugs: hypersensitivity to any component of the drug. Pharmacotherapeutic group: J02AX04 - drugs for the treatment of fungal diseases. Arteriosclerotic Coronary Artery Disease during or slurping eating, adults 400 - 800 mg / day, divided into 4 admission, average daily dose - 400 mg (100 mg 4 g / day) in severe cases the daily dose increased to 800 mg (200 mg 4 years / day), children 1 - 14 years normal average daily dose - 200 - 400 mg (50 - 100 mg 4 g / day) for children 2 - 12 months of daily dose of 25 mg / kg / day, divided into 4 admission, the patient may take the drug for 1 month, with Mts Nitroxoline infections can prescribe repeated courses lasting 2 weeks with two-week break (the treatment may take several months) for patients with moderate degree of renal insufficiency (creatinine clearance above 20 ml / min) designate half the usual daily dose, with liver failure should be given half The usual daily dose. Method of production here drugs: Table., Coated tablets, 50 mg slurping . The main pharmaco-therapeutic effects: has antibacterial activity against a slurping range of Gr (+) and Gr (-) m / s and mushrooms, and its antibacterial and antifungal spectrum covers most m / c that cause urinary tract infections.
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