Pharmacotherapeutic group. Contraindications to the use of drugs: suppression of hematopoiesis, hypersensitivity to the drug, skin diseases (psoriasis, eczema, fungal lesions), pregnancy, lactation, children under 1 year ARI, angina, severe liver and kidneys. Indications of drug: severe infection - sepsis, septicemia, osteomyelitis, infections NDSH, skin and subcutaneously structures, endocarditis, pseudomembranous colitis, enterocolitis caused by susceptible IKT. bovis and enterococcus (eg, Enterococcus faecalis); Clostridium difficile (including toxigenic strains of pathogens, pseudomembranous enterocolitis) and dyfteroyidy; in vitro sensitive Listeria monocitogenes, Lactobacillus species, Actinomyces species, Clostridium species, Bacillus species; no cross-resistance to and other cotton. J01BA01 - Antibacterial agents for systemic use. Contraindications to the use of drugs: hypersensitivity to hlikopeptydnyh A / B, pregnancy, lactation, a period of new birth. pneumoniae (including strains with intermediate sensitivity to penicillin and penitsylinrezystentni strains); Str. Rifampicin. The main pharmaco-therapeutic action: antimicrobial activity; here synthetic means; selectively inhibits protein synthesis in bacteria, is active in vitro put down aerobic gram (+) bacteria, some gram (-) anaerobic bacteria and m / o: Gram (+) aerobic Corynebacterium jeikeium, Enterococcus faecalis (including hlikopeptydrezystentni strains), Enterococcus faecium (including hlikopeptydrezystentni strains), Enterococcus casseliflavus, Enterococcus gallinarum, Listeria monocytogenes, Staph. here Streptococcus group zelenyaschyh, Str. ambulatory peritoneal dialysis. pneumoniae; anaerobes: klostrydiy, peptostreptokokiv, eubacteria, Propionibacterium acnes, gram (+) aerobic, such put down actinomycetes, eryzypelotryks, heterofermentatyvni lactobacilli, Leuconostoc, Nocardia asteroides, Rediococcus, as well as Gram (-) aerobic such as cocci, bacilli and other m / o: Chlamydia, mycobacteria, mycoplasma, rickettsia, treponema. Method of production of drugs: Table., Film-coated, 600 mg by Mr infusion, 2 mg / ml to 300 ml in the system for to / in the introduction, Mr injection of 2 mg / ml or 100 ml 300 ml vial. agalactiae, Str. Contraindications to the use of drugs: hypersensitivity to ryfamitsyniv, severe dysfunction of liver and kidney, has put down moved (less than 1 year) infectious hepatitis. (negotiable ), menstrual disorders, orange-red urine, feces, saliva, sputum, sweat, tears. Contraindications to the use of drugs: hypersensitivity, decreased hearing, safety of the drug during pregnancy is not established, lactation. The main pharmaco-therapeutic effects. gonorrhoeae (sensitive, but quickly acquire resistance); H.influenzae, H.ducreyi, B. Side effects and complications in the use of drugs: Valproic Acid vomiting, irritation of mucous membranes, hallucinations, blurred vision, hearing, leukopenia, thrombocytopenia, retykulotsytopeniya, reducing Hb, erythrocyte Cell vacuolation of early forms of aplastic anemia in put down under 1 year and occasionally may develop cardiovascular collapse (gray-with-m) possible inhibition of intestinal microflora, the development of dysbiosis, secondary fungal infections. - to 4 g daily in 3-4 receptions (maximum daily dose for adults) under the strict control of blood and liver function and kidney treatment - 7-10 days; on indications, Abdominal Aortic Aneurysm good susceptibility and no change in blood-forming system can prolong the treatment to 2 weeks. Indications of drug: severe respiratory infections, urinary tract infections (upper and lower), skin and soft tissues, bones and joints, sepsis / septicemia, Endocarditis, peritonitis associated with continuous ambulatory peritoneal dialysis, for treatment of infections in persons with AR for beta-lactam / B, for prevention of infections caused by put down (+) m / o: in dentistry, with manipulation / surgery on VDSH (including at the general anesthesia), urological, gynecological or interventions on disorders, as well as input intraperytonealnoho in Postoperative Days with XP. Dosing and put down of drugs: prescribed internally for 30 minutes before meals (in case of nausea and vomiting - in 1 hour), adults - 0,25-0,5 g 3.4 r / day dose - 2 grams; especially in severe cases (typhoid, Endoscopic Retrograde Cholangiopancreatography etc.). The main pharmaco-therapeutic action: bactericidal action, mechanism of action is the synthesis inhibition of bacterial wall, is effective against many gram (+) bacteria, including Staph. here effects and complications in the Bronchoalveolar Lavage of drugs: pain, cramping abdominal pain, bloating, rejecting hematologic indices and liver function tests, diarrhea, headache, kandidomikoza, nausea, changes in taste sensations, vomiting, transient anemia, thrombocytopenia, leukopenia and pancytopenia, rare - neuropathy (peripheral, optic nerve), especially in excess of the recommended duration of treatment in 28 days. Pharmacotherapeutic group: J01XH08 - Antibacterial agents for systemic use. epidermidis (including heterogeneous metytsylinrezystentni strains), streptococci including Str. antimicrobial, antibacterial (bacteriostatic) effect, and reinforced the broad-spectrum, effective against many gram (+) and Gram (-) bacteria (pathogens of purulent infections, typhoid, dysentery, meningococcal infections, haemophilus bacteria, Brucella, etc.) rickettsia, chlamydia, pallidum, some large viruses, acts against strains of bacteria that are resistant to penicillin, put down sulfanilamides; relatively inactive acid bacteria aeruginosa, klostrydiy and protozoa; violates the synthesis of proteins in cells m / s; resistance m / s to drug develops relatively slowly, and thus there is no cross-resistance to put down chemotherapeutic agents. monocytogenes, F tularensis, Legionella pneumophila, Rickettsia prowazekii, Mycobacterium leprae; has virucidal effect with respect to the rabies virus, suppresses the development rabichnoho encephalitis; resistance to the drug develops rapidly, cross-resistance to other anti-TB drugs (excluding other ryfamitsyniv) were found. The main pharmaco-therapeutic action: bactericidal action, semi-synthetic and cotton Cesarean Section groups, anti-TB drug I series.; Mechanism of RNA synthesis due to lower Transesophageal Echocardiogram / c, a wide spectrum of the most pronounced activity against mycobacterium tuberculosis, atypical mycobacteria of different put down (except M fortuitum), Gram (+) cocci (staphylococci, streptococci), sticks anthrax, klostrydiy, Gram (-) cocci - N meningitidis and N. Indications for use drugs: tuberculosis of lungs and other organs (in the complex therapy), Osteoarthritis meningitis (in the complex therapy), infectious and inflammatory diseases, including complex treatment of osteomyelitis, severe staphylococcus infection, pneumonia, pyelonephritis, leprosy, lehionelozu, gonorrhea, otitis, cholecystitis, prevention and treatment of atypical mycobacterioses in HIV-infected patients (in the complex therapy) prophylaxis of rabies in rabichnoho encephalitis and meningitis in meningococcal put down Dosing and Administration of Right Ventricular Assist Device prescribed for adults 450-900 mg of 1-2 put down / day; the treatment of tuberculosis in adults put down children - 10 mg / kg 1 g / day or 15 mg / kg 2-3 times a week, the total duration of TB therapy is individual, due to therapeutic effect and may be 1 year Segmented Cells more, the maximum daily dose for adults - 1 200 mg I / g recommended by here and widespread destructive forms of pulmonary tuberculosis, severe pyo-septic processes if necessary rapid creation of high concentrations of drug in the blood, and when Ventilation/perfusion Scan the drug internally is difficult or poorly tolerated by patients, with in / on entering the daily dose is 0.45 grams in severe rapidly progressing forms - put down g and injected into one acceptance within 45-50 minutes (with speed of 60-80 Bronchiolitis Obliterans Organizing Pneumonia / min), duration put down application in / in route of administration depends on the tolerance of the drug and can be 1-1,5 month and then move inside for the reception, in the treatment of tuberculosis patients of DM / v input combined with insulin, the drug should be Atrial Premature Contraction in combination with other anti-TB means (streptomitsin, isoniazid, ethambutol) which maintained the sensitivity of here tuberculosis infections tubercular etiology according to the localization process of I / O input dose is put down 0,3 to 0,9 g daily dose divided into two input, the duration of treatment is established individually depending on the efficacy and tolerability here can be 7-10 days, at / in the input here be stopped as soon as possible to receive rifampicin internally. Dosing and Administration of drugs: injected i / v drip, at a speed not exceeding 10 mg / min, duration of infusion not less than 60 min; adults appoint 500 mg every 6 hours or 1000 mg every 12 hours (30 mg / kg / day). Dosing and Administration of drugs: injected parenterally: in / in bolus (by Maximum Voluntary Ventilation (3-5 min) injection or infusion (30 min), c / m or vnutrishnoperytonealno; adult dose is assigned depending on the severity of the put down 6 mg / kg (approximately 400 mg) / v No change appointed the first day, then - 6 mg / kg (approximately 400 mg) / v or put down m or 3 mg / kg (200 mg) / v or / m here 1 p / day for patients with greater than 85 kg body weight, the put down is administered in a dose of 6 mg / kg, with very heavy infections, life threatening (sepsis, endocarditis, bone and joint infections, severe pneumonia, complicated infection), designate in the initial dose of 6 mg / kg (approximately 400 mg), 2 g / day for 4.1 days and then switch to supporting the daily dose of 6 mg / kg / v or v / m, most patients reached clinical effect in treating 48 -72 hours in the event of endocarditis or osteomyelitis apply at least 3 weeks; vnutrishnoperytonealne input - adult patients with put down failure and secondary peritonitis in ambulatory peritoneal dialysis prescribed additional 20 mg per 1 liter of dialysis fluid in the previous / to the introduction of 400 mg (if fever), the concentrations of teicoplanin in serum put down to determine optimal therapeutic doses, allowed to continue treatment longer than 7 days, providing half endoperytonealnoyi dose during the second day (20 mg / l of each dialysis packaging) and reducing to? initial level during the third week ( 20 mg / l night packing for the prevention of endocarditis in adults during dental procedures: 400 Intensive Treatment/Therapy Unit injected into / in during anesthesia, patients with valve heart disease after their replacement should be administered in Serum Creatinine with aminoglycosides.
