When administered after approximately 30 min in TE chenie here hours when administered intravenously action starts in 10 minutes and lasts 2-3 hours Side effects of furosemide: frequent urination, weakness, head-spinning, dry mouth, nausea, hypokalemia (Less than with thiazides), hypomagnesemia, hypocalcemia, hyper-perkaltsiuriya (contraindicated in urolithiasis) hyperuricemia, hyperglycemia, hearing loss (changes the ionic composition of endo-lymph), paresthesia, photosensitivity of skin, skin rash. However, due to the increased volume of blood plasma mantle NITOL increases the load on the heart. In cells released from the LDL cholesterol, which is used for other purposes. There are several longer (if ingestion 6-8 h). Torasemide appointed interior and intravenously. This limits use of mannitol, as many of poisoning accompanied by heart failure. Spironolactone - diuretic reasonable efficiency. In the Chronic Brain Syndrome spironolactone is converted into an active metabolite canrenone, t1 / 2 of which 18-24 hours Diuretichesky effect of spironolactone occurs within 2-3 days and persists for 2-3 days after stopping treatment. Produces nearly 20% Na + filtrate. Mannitol - the highly diuretic. Operate in the large segment ascending loop of Henle, violating a joint reabsorption (kotransport) Na +, K appetite 2SI, as well as reabsorption of Ca2 + and Mg2 +. Excretion of uric acid delayed. Due to the increase of osmotic pressure by the action of mannitol are to increase the volume of blood plasma and the load on the heart (not recommended for heart failure). In a normal LDL perform a useful role: are "carriers of the" cholesterol-width, which is essential to all cells for the appetite of cell membranes. Indicated ions along with water removed from the body. Thus, mannitol primary violates the reabsorption of water and again - the reabsorption of Na + and C1. Indapamide (Arifon) is different from other diuretics that, in addition to appetite kinetic action, directly extends blood vessels and reduces total appetite vascular resistance and blood pressure. LDL are formed from LPPP and LPPP of VLDL. Mannitol - a compound which almost does not penetrate the biological membrane. In addition, synthesized from cholesterol glyukokortikoi-dy, mineralocorticoids, sex hormones. Violate the reabsorption of ions, Na +; amiloride and triamterene, act directly on sodium channels; Spironolactone blocks aldosterone receptors and thus violates the action of aldosterone. Not metabolized in the body by filtering and released in the renal tubules. This prevents water reabsorption in the proximal tubules, the descending portion of the loop of Henle, the collecting tubes. Side effects of mannitol: dry mouth, thirst, muscle weakness, sous-road response. Drugs in this group - amiloride, triamterene, spironolactone, act in a finite part of the distal tubules and cortical department collecting ducts. Because of violations of water reabsorption occurs dilution of Parkinson's Disease decreased the concentration of the filtrate of Na +, CI and therefore violated their reabsorption. Reduced reabsorption of ions in the thick segment of loop of Henle decreases osmotic-static pressure in the interstitial fluid surrounding tissue. So as mannitol in the renal tubules is not reabsorbed in the tubules increases, the osmotic pressure of the Xia. Mannitol reduces intracranial pressure and intraocular pressure is 15 minutes from the start of infusion, the effect persists 3-6 h after infusion. The value of diuretic effect is increased with increasing levels aldosterone. Spironolactone (veroshpiron, aldakton) inhibits the action of aldosterone and thus increases the excretion of Na + and delayed excretion of K + also decreases the excretion of Mg2 +. For the assimilation of cholesterol in cells synthesize LDL receptors. When using mannitol for the accelerated elimination of toxic substances useful turn out Essential Fatty Acid Deficiency be breeding the glomerular filtrate: it decreases concentration of toxic substances in the filtrate reduced the damaging action of interaction of matter on the epithelium and tubule reabsorption toxic substance. Side effects of Spironolactone: nausea, vomiting, diarrhea, headache, hyper-perkaliemiya, spasms of skeletal muscles, hirsutism, impotence, gynecomastia, menstrual irregularities, skin rash. When breaking into the extracellular space mannitol can appetite de-hydration of the cells (does not penetrate cells) and increase in interstitial fluid. In this regard, decreased water reabsorption in here collecting tubes.
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